1 Features

• Integrated Signal Chain for ECG, Pace Detection,

and Respiration Measurement

• ECG Receiver

– Four high resolution channels at low power of

0.42mW/channel

– Flexible four leads selectable from six

electrodes

– Programmable gain: 1.25 to 9

– Input-referred noise: 4μVPP in 150Hz BW

– Differential input range: ±1V with Gain = 4

– CMRR: -140dB

– Data rate: 125SPS to 128kSPS

• Pace Detection

– On-chip digital pace detection algorithm on

programmable two leads

– High-speed 128kSPS pace output on two

channels for software pace detection

• Respiration

– Low-noise of 24mΩPP with 2kΩ body

impedance and 1kΩ defibrillator protection

resistor on each electrode

– Supports Sine and Square wave excitation

• Other Features

– Built-in right leg drive amplifier steerable to any

electrode

– DC lead-off detection, AC lead impedance

detection, Wilson Center Terminal (WCT),

Goldberger Central Terminals (GCT), test

signals

– Battery voltage monitoring

– Flexible power-down and standby modes

– Built-in oscillator, PLL, and reference

– 1k sample main FIFO and 2k sample pace

FIFO

– SPI-compatible serial interface

– Analog supply voltage 1: 3.15V to 5.25V

– Analog supply voltage 2: 1.7V to 1.9V

– I/O supply voltage: 1.65V to 3.6V

• Supports systems meeting AAMI EC11, AMI

EC13, AMI EC38, IEC60601-1, IEC60601-2-25,

IEC60601-2-27, and IEC60601-2-51 standards

2 Applications

• Medical instrumentation (ECG, EMG, and EEG):

– Bedside patient monitoring and diagnostic ECG

– Portable telemetry

– Holter monitor and multi-lead patch

• Event, stress, and vital sign monitors:

– ECGs

– AEDs

– Telemedicine Bispectral Index (BIS)

– Evoked Audio Potential (EAP)

– Sleep study monitor

3 Description

The AFE1594 is a family of multichannel,

simultaneous sampling, 24-bit, delta-sigma (ΔΣ)

analog-to-digital converters (ADCs) with built-in

programmable gain Instrumentation Amplifiers (INAs),

internal reference, and an on-chip PLL. The AFE

supports digital pace pulse detection, thoracic

impedance measurement and incorporates all of

the features that are commonly required in medical

electrocardiogram (ECG) and electroencephalogram

(EEG) applications. Multiple AFE159x devices can be

cascaded in high channel count systems. With high

levels of integration and exceptional performance,

the AFE159x enables the development of scalable

medical instrumentation systems at significantly

reduced size, power, and overall cost.